Mariam Issoufou was born in 1979 in Saint-Étienne, France, and grew up in Niger. She first studied computer science in the United States and worked for several years as a software developer. In 2013, she completed a second degree in architecture at the University of Washington in Seattle. The following year, she founded her own architecture firm in Niamey, and in 2023, she opened a branch in New York. Since 2022, Issoufou has been Professor of Architectural Heritage and Sustainability at ETH Zurich.